ASP Isotopes Inc. (ASPI) Material Update

Date of Event: November 5, 2025

The U.K. subsidiary, Quantum Leap Energy Ltd., has commenced early engagement for regulatory pathways with U.K. nuclear regulators.

This Form 8-K reports a material business development concerning regulatory progress.

Key Investor Points:

• Strategic Initiative: U.K. subsidiary initiating early regulatory engagement.
• Listing: Common Stock trades on The Nasdaq Stock Market under ticker ASPI.
• Status: Registrant is an Emerging Growth Company.
• Note: This filing does not contain